The Cayenne Coupe’s pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The Murano doesn’t offer pre-crash pretensioners.
Both the Cayenne Coupe and Murano have child safety locks to prevent children from opening the rear doors. The Cayenne Coupe has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The Murano’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The Cayenne Coupe has a standard Multi-collision Brake System, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The Murano doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.
To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the Cayenne Coupe. But it costs extra on the Murano.
A passive infrared night vision system optional on the Cayenne Coupe helps the driver to more easily detect people, animals or other objects in front of the vehicle at night. Using an infrared camera to detect heat, the system then displays the image on a monitor in the dashboard. The Murano doesn’t offer a night vision system.
The Porsche Cayenne Coupe’s rear backup camera has a standard washer for maintaining a clear view under various conditions. In contrast, the Nissan Murano does not offer a rear camera washer, meaning its effectiveness relies on manual cleaning by the user when necessary.
Both the Cayenne Coupe and Murano have Rear Cross Traffic Alert, but the Cayenne Coupe has automatic rear cross-traffic braking (automatically applies the brakes) to better prevent a collision when backing near traffic. The Murano’s Rear Cross Traffic Alert doesn’t automatically brake.
Both the Cayenne Coupe and the Murano have standard driver and passenger frontal airbags, front and rear side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning and driver alert monitors.

